RESEARCH
NOTES
& METHODS
A running record of analytical methods, evidence maps and quality explainers from the Stratum bench.
Reading a peptide COA: what each line actually proves
A certificate of analysis is a claim sheet, not a guarantee. Here is what HPLC area%, mass spec identity, endotoxin and sterility lines each do and do not establish — and which questions to ask when a line is missing.
QUALITY · COASWhat HPLC purity does and does not tell you
Area percent is the most quoted and least understood number on a peptide certificate. A short methods note on detection thresholds, co-elution, and why two labs can honestly report different purity for the same vial.
QUALITY · METHODSBPC-157: the state of the preclinical evidence
A pentadecapeptide derived from a gastric juice protein, with a large rodent literature and a thin clinical one. A neutral map of where the evidence stands, what models dominate it, and where the gaps are.
COMPOUNDS · EVIDENCEBatch traceability as a buying criterion
The cheapest signal of a serious supplier is not price or purity number — it is whether a certificate can be tied to the exact unit you received. How to test traceability before you buy.
QUALITY · SOURCING